Side effects of Anadrol

Properties of Anadrol

The active substance (steroid oxymetholone) is a modified form of dihydrotestosterone (biologically active form of testosterone in the human body). It has strong anabolic (anabolic index: 320% of endogenous testosterone) and moderate androgenic activity (androgenic index: 45% of endogenous testosterone). It is considered one of the strongest oral anabolic steroids, among those used for sports purposes.

Anadrol, due to its strength, is mainly recommended for experienced athletes. It is only not recommended for women, as even at relatively low doses there is still a risk of virilisation. However, experienced female athletes are known to take oxymetholone preparations, but only in low doses not exceeding 50 mg per day, so as not to cause the development of androgenic side effects.

Anadrol promotes enhanced anabolic processes in relation to muscles. The main effect is a pronounced increase in muscle mass. Athletes also appreciate the effects of increased strength and endurance, improved joint and ligament function and elimination of joint pain. During use, increased protein production, decreased function of sex hormone binding globulin, increased haematopoiesis and stimulation of erythropoietin hormone production have been observed.

Potential side effects include estrogen/progestogen, androgen and hepatotoxicity (moderate hepatotoxicity, which is a limitation for long-term use beyond 6-8 full weeks). Side effects such as water retention, hypertension, gynecomastia, increased aggressiveness, acne, baldness, suppression of testosterone production, testicular atrophy and some others are particularly likely in cases of misuse.
To preserve the quality of the drug, storage of Oxymetholone Olimp Labs should be at a temperature no higher than room temperature, in a dark and non-humid place. For safety reasons, it should be stored out of the reach of children and pets.

Properties of Anadrol

How to take Anadrol

Based on reviews and experience of using the product, it is possible to gain up to 10-15 kg of muscle mass per course. Its many different effects make it important not only for bodybuilding, but also for almost all other high-impact sports.

Olimp Labs Oxymetholone, like its analogues, is potent enough to be the only steroid taken in a course. However, use in combination with other steroid preparations is more common. Depending on the experience and goals of the individual weightlifter, combinations with testosterone, stanozolol, methenolone or, for example, boldenone may be effective.

For athletes, we generally recommend daily doses of Anadrol in the range of 50-100 mg (with good tolerance, doses of up to 100-200 mg daily are allowed). The frequency of administration is daily, as the steroid does not have a long duration of action (it is active up to 15 hours after administration).
Immediately after completion of the course, post-treatment is mandatory. PKT may effectively involve the use of clomiphene citrate or tamoxifen. The duration of post-treatment and the doses required (on average 3 weeks within 10-40 mg tamoxifen or 50-150 clomiphene citrate daily).

Anadrol Combination Course (example): with Testosterone Enanthate and Boldenone for significant increase in muscle mass in experienced lifters. A course of up to 10 weeks can be followed. Doses and course schedule are on average 100 mg oxymetholone per day (weeks 1-6), 500 mg testosterone enanthate per week (1-6 weeks) and 600 mg boldenone per week (1-6 weeks). To prevent side effects, mestrolone and anastrozole should also be taken during treatment and tamoxifen during post-treatment and tamoxifen during treatment.

How to take Anadrol

Interaction with oxymetholone

Oxymetholone combines well with some injectable agents, but should not be combined with 17-alpha alkyl steroids as this would increase liver stress. Anapolon is often used for what is called a “quick start” (anabolic effects occur very quickly) and provides significant strength and body weight gains in the early stages of a course, while other drugs in the stack gently increase concentration. The combination provides a better effect because oxymetholone lowers the concentration of sex hormone-binding globulin while increasing the free fraction of the other hormones, thus acting as a synergist of several drugs simultaneously. Since anapolone has a low affinity for androgen receptors[9] (it binds weakly to them), other potent androgenic hormones can exert their full effect by interacting with these receptors without competing with anapolone.

To increase muscle mass, anapolone is combined with testosterone, boldenone, primobolan, or trenbolone. To increase potency, it is often used in combination with various testosterone esters. A very effective combination is the combination of oxymetholone with stansolol suspension, and athletes notice an immediate increase in strength. However, it should be noted that such a combination carries a high risk of injury, especially for those with chronic injuries.

Oxymetholone is almost never used for drying and sculpting because it causes significant fluid retention.
Competition level bodybuilders often take a single dose of 100-250 mg of oxymetholone per day. This adds fullness to the athlete’s muscles.

Interaction with oxymetholone


In general, oxymetholone is one of the most toxic anabolic steroids and frequently causes side effects. Pronounced hepatotoxicity is difficult to justify, even given its potent anabolic effects and relatively low cost. The safest dose of the drug is 100 mg/day (or less), which has been confirmed by studies.
Because of the 17-alpha alkyl group in the drug’s structure, it passes through the liver without being broken down, which is why anapolon is toxic to the liver. In 30-week studies in which participants took oxymetholone at doses as low as 50 mg/day, hepatic side effects were common. It is one of the most liver toxic drugs.

It should also be noted that oxymetholone is not converted to estrogen, but can cause fluid retention, gynecomastia, hypertension, and a number of other side effects. It is believed that anapolon can bind to and activate estrogen receptors. Therefore, estradiol levels should be monitored during treatment and aromatase inhibitors should be used accordingly. It should be noted that oxymetholone has no progestagenic effect and there are no studies that clearly indicate such an effect. The drug itself is a dihydrotestosterone derivative.

In some cases (at high doses) it may cause diarrhea, loss of appetite, and mild nausea. Oxymetholone inhibits testosterone production less than most steroids.